Snehal Sonani
Dustavrana (Chronic/ non-healing/ contaminated ulcer) is a frequently encountered problem in present era commonly as a complication of trauma and pathological insult. Ayurveda had stated Vrana Shodhana and Vrana Ropna as a treatment modality which is mentioned under the Shasti Upkramas. Number of drugs known to Ayurveda since Vedic era is increasing from time to time. Here folklore drug Katupila, which can be easily available and useful for Vrana Shodhana and Ropana was introduced for the treatment of non-healing ulcers. So, open single arm Clinical Trial Study on minimum 30 patients of Dusta Vrana were treated with local application of Katupila Nirudhhalepa (Katupila Patra Churna and Honey). by clinical analysis, Shodhana property of Katupilla Nirudhhalepa is established by absence of necessity of mechanical debridement in all the 30 patients, though they have reported with different grading of slough. Ropana property is indicated by pharmacological evaluation, that it consists many of ingredient i.e. alkaloids, terpenoids, flavanoids etc and also antibacterial activity which are promoting factors for wound healing process.
